BDBM477927 (1S,5S,6S)-3-amino-5-(2-fluoro-5-((5-(2-propyn-1-yloxy)-2-pyridinyl)ethynyl)phenyl)-N,N,5-trimethyl-2-thia-4-azabicyclo[4.1.0]hept-3-ene-1-carboxamide::US10889581, Example 130
SMILES CN(C)C(=O)[C@]12C[C@H]1[C@](C)(N=C(N)S2)c1cc(ccc1F)C#Cc1ccc(OCC#C)cn1
InChI Key InChIKey=MOAJIFLFRHPNCU-GPUOULLFSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 477927
Affinity DataIC50: 161nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair